Gene Editing & Cell Therapy: Revolutionizing Medicine Through Genetic and Cellular Engineering

Ahmed Ansari^1*, Ali Amin²

¹Department of Biology, College of Science, Jazan University, Kingdom of Saudi Arabia Zoology

²Department, Faculty of Science, Mansoura University, Mansoura, Egypt

*Corresponding Author

Ahmed Ansari, Department of Biology, College of Science, Jazan University, Kingdom of Saudi Arabia, E-mail: ahmed@ansari.sa

Abstract

Gene editing and cell therapy represent transformative approaches in modern medicine, enabling precise manipulation of genetic material and cellular functions to treat a broad range of diseases, including genetic disorders, cancers, and degenerative conditions. Advances in gene editing technologies such as CRISPR-Cas9, TALENs, and base editing, combined with innovations in cell therapy-including hematopoietic stem cell transplantation, CAR-T cell therapy, and induced pluripotent stem cells (iPSCs)-have propelled these fields into clinical reality. This article reviews the principles, methodologies, clinical applications, challenges, and future directions of gene editing and cell therapy. It also discusses ethical considerations and regulatory frameworks essential for their responsible implementation.