Transplantation & Organ Technology Advances Challenges and Future Directions

Pruett Park^1*, Sesan Wolf²

¹Department of Surgery and Internal Medicine, University of Minnesota School of Medicine, USA

²Department of Medicine, University of Minnesota, USA

*Corresponding Author

Pruett Park, Department of Surgery and Internal Medicine, University of Minnesota School of Medicine, USA, E-mail: pruett@park.edu

Abstract

Organ transplantation has transformed the management of end-stage organ failure, offering life-saving treatment for conditions such as liver, kidney, heart, and lung failure. However, donor organ shortages, rejection, and complications from immunosuppression remain significant hurdles. Recent advancements in organ technology—including organ preservation, bioengineering, xenotransplantation, and artificial organs—are reshaping the landscape of transplantation medicine. This article reviews the current status of organ transplantation, explores innovations in organ preservation and engineering, discusses challenges, and evaluates future prospects to address global transplant needs.